Aim: The present study aimed to evaluate and compare the efficacy and safety of oral bromelain, a natural enzyme complex with oral diclofenac sodium in 3-Piece Gift Set managing pain and swelling after mandibular third molar surgery.Materials and methods: A total of 40 patients were randomly divided into two groups, the bromelain group (n = 20) and
Insomnia and sexual dysfunction associated with severe worsening of the quality of life in sexually active hysterectomized women
Introduction: Hysterectomy is a common gynecologic surgery carried out to remove the pathologic uterus.Objective: To establish if sleep disorders and sexual function are associated with deterioration of the quality of life (QoL) in hysterectomized and sexually active women.Methods: A cross-sectional study was carried out with inhabitants from two c
Mitotic CDK1 and 4E-BP1 II: A single phosphomimetic mutation in 4E-BP1 induces glucose intolerance in mice.
ObjectiveCyclin-dependent kinase 1 (CDK1)/cyclin B1 phosphorylates many of the same substrates as mTORC1 (a key regulator of glucose metabolism), including the eukaryotic initiation factor 4E-binding protein 1 (4E-BP1).Only mitotic CDK1 phosphorylates 4E-BP1 at residue S82 in mice (S83 in humans), in addition to the common 4E-BP1 phospho-acceptor s
Nature enclosures: historic peasants versus public and private conservation units of the Paraguay River in the Pantanal wetlands of western Brazil
Conservation policy which discriminates against historic fisher-farmers of the Paraguay River of western Brazil is questioned using radical environmental history and critical global political ecology perspectives.Over the last three decades enormous areas located along the Paraguay River in the Pantanal wetlands biome have been transformed into pub
SEMA6A drives GnRH neuron-dependent puberty onset by tuning median eminence vascular permeability
Abstract Innervation of the hypothalamic median eminence by Gonadotropin-Releasing Hormone (GnRH) neurons is vital to ensure puberty onset and successful reproduction.However, the molecular and cellular mechanisms underlying median eminence development and pubertal timing are incompletely understood.Here we show that Semaphorin-6A is strongly expre